The report
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Three parts, twelve chapters. Each section opens on a short abstract; the full text is one tap away. Every chapter carries a single recommendation.
The Emerging Reality
Chapter I. Introduction
5 sectionsFuturism in Biomedicine: The Mosaic Metaphor · Arc of Medicine: Historical Threads · Physicians Evolving: Hippocrates 1.0 – 4.0 · The Hippocrates 4.0 Physician: Plural and Fluid Identities · The Attitude of This Report
Chapter II. The Biomedical Frontier
5 sectionsNew Biologies · Theranostics: Near-Term to Visionary · Editing Germline, Deciphering Brain, Extending Lifespan, Conquering Space · The Discovery Process: AI as Investigative Tool · The Translational Gap
Chapter III. Emerging Modes of Medicine
3 sectionsA Matrix of Healthcare Paradigms · Machine Intelligence Reframes the Medical Landscape: Blind-Spot Free Care · Learning Health Systems
Technoscientific Disruption: Multilevel, Multimodal · Complexity Science Comes to the Fore · AI Intelligence Ecosystem: From Data Procurement to Data Curation · Physical AI: A Gradient of Autonomy · Statistics, Mathematics and Physics Transform Biomedicine
Pursuit of N-of-1 Medicine: Humans Fill the Irreducible Gap · Biomedical Digital Twins · From Repair to Preemptive Medicine · On the Road to Holistic/Integrative Medicine · Rethinking the Evidence in Evidence-Based · The Patient of 2050
The Physician Redefined
Intelligences Meet: The Human Advantage · Recasting Physicians in the Age of Machine Intelligence: Guardian of Health · Four Physician Identities: Contours of the Hippocrates 4.0 Physician
The Physician Creative: Explorer and Designer · Reimagining the Biomedical Research Enterprise · The Curious Physician: Nurturing Wonder
Chapter VIII. The Consilient Physician
4 sectionsBridging Knowledge Domains: Consilience · Counterbalancing Specialty Fiefdoms · An Embrace of Distributed Intelligence: Horizontal Care · Interprofessional Education: Reifying Consilience
Chapter IX. The Transcendent Physician
5 sectionsThe Human Factor · Rehumanizing Medicine: Medical Virtue · Complexity, Data, and the Limits of Prediction · Judgment and Wisdom: Ethical Decision-Making, Evaluating Truth · The Problem Solver: Educating to Critical Thinking
Chapter X. The Global Physician
5 sectionsThe Socially Responsible Physician · Population Health Frontier · Bridging Mankind: Planetary Health · Global Health Governance, Security, Ethics · Mandatory Global Training Experiences
The Transition
Hardwiring the Mid-21st Century Physician: The Future Curriculum · The Simulation Frontier · Revisiting Lifelong Learning: The Adaptable Physician
Chapter XII. Pursuing Interconnectedness
2 sectionsConnecting Medical Academy, Organizations, and Industry · Cooperative Advancement of Medical Education